DUI expungement or sealing is only possible in Florida for one case. You might be able to get the DUI reduced to Reckless Driving, or it’s possible that the charges will be dismissed. You also could win acquittal in court. If the DUI charge leads to a conviction, you cannot expunge it. Since you have to be adjudicated on a DUI in Florida, you could move to have it sealed.
Ideally, your lawyer would successfully negotiate to have the charged reduced to a lesser charge such as Reckless Driving. That’s possible if there’s an evidentiary problem (e.g. no probable cause for the initial traffic stop) or if the state can’t prove DUI. Usually the defense for DUI is based on a pretrial evidentiary problem for the state or lack of proof of faculty impairment.